News & Press Releases
The course will provide didactic and hands on training in the use of swine as biomedical research models. The lectures will include: handling, husbandry, animal welfare, anesthesia, analgesia, perioperative care, animal models and surgical techniques. Students will perform basic procedures in swine including: venipuncture, injections, intubation, surgical cut-downs, thoracic and abdominal surgical approaches.
Sinclair Research Center and Sinclair BioResources have recently contributed to a special issue of Toxicologic Pathology (Volume 44, Number 3, 2016) titled Swine in Translational Research and Drug Development. This issue focuses on the most recent developments of the use of swine, particularly miniature swine, in preclinical research; it also delves into the potential of future use of miniature swine in translational research and drug development. SRC and SBR contributed to the collection of background clinical and histopathological observations, vital to the interpretation of test article-related findings, in the article ”Miniature Swine Breeds in Toxicology and Drug Safety Assessments: What to Expect during Clinical and Pathology Evaluations”; they additionally contributed to the article “Background Pathological Changes in Minipigs: A Comparison of the Incidence and Nature among Different Breeds and Populations of Minipigs.”
Book Release – A third edition of: Swindle, MM: Swine in the Laboratory: Surgery, Anesthesia, Imaging, & Experimental Techniques
A third edition of: Swindle, MM: Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, has been released by CRC Press in Boca Raton, Florida. To purchase, click the link above.
Sinclair BioResources is proud to offer a unique and comprehensive pdf of normal clinical pathology and biological data on our lineages of miniature swine. Over 80 useful tables are presented in user friendly format on the 130 page CD. Included are commonly requested Model Uses, Body Weights, Hematology, Serum Chemistry, Urinalysis, ECG, Organ Weights, Histopathology, Blood Glucose, Ocular, Diet/Feeding, Reproduction, Heart/Vascular, Dermal, Dental, Cartilage/Bone, Miscellaneous, and searchable References. This massive effort collates and summarizes data collected over many years by Sinclair Research and Sinclair BioResources and will be updated regularly as new data is incorporated.
The latest addition to the Homeostasis model series, Trauma Models in Swine, is now available...
Miniature swine models of hemorrhage, hemostasis, shock, and trauma are commonly in use to study the pathophysiology of blood loss and look for novel means for saving lives.